Halotestin (Fluoxymesterone)
Introduction and Clinical History
Halotestin is the trade name for Fluoxymesterone, an oral anabolic steroid known for its exceptional androgenic potency. Halotestin was first described in 1956 and introduced for medical use in 1957. It was developed by Upjohn and marketed as Halotestin (in the US) and Ultandren (in Europe) among others. Medically, fluoxymesterone was used for various indications: in men, it treated testosterone deficiency (hypogonadism) and delayed puberty, and in women, it was prescribed (at lower doses) for breast cancer and sometimes as part of anemia treatment. It is a very powerful androgen, roughly 5-19 times as potent as testosterone in anabolic effect, and anecdotally even more in androgenic effect (the anabolic:androgenic ratio varies by assay, but Halotestin is extremely androgenic).
Halotestin’s high potency comes from structural modifications: it’s essentially testosterone with a 9α-fluoro group and 11β-hydroxyl group, plus 17α-methylation for oral bioavailability. These tweaks make it non-aromatizable and resistant to metabolism, but also impart unique effects on the body (like interaction with glucocorticoid enzymes).
While effective in certain medical scenarios, fluoxymesterone’s toxicity and side effects led to it being less favored over time. It is still available by prescription in some places for hypogonadism or refractory anemia, but it’s rarely used now, in part due to its side effect profile (especially liver and cardiovascular strain).
In sports and bodybuilding, Halotestin gained a reputation as a ferociously strong drug for strength and aggression. Its use has been predominantly in strength sports or as a pre-contest hardener for bodybuilders. Because Halo doesn’t aromatize, it doesn’t cause water retention; thus it can enhance strength and hardness even on a calorie deficit. However, it builds little actual muscle mass – it’s not a mass gainer steroid. Fluoxymesterone is considered one of the most androgenic steroids, and accordingly, its effects (both desired and adverse) are intense. Historically, powerlifters and fighters have used Halotestin in the weeks leading up to competition for an extra edge in aggression and strength. It’s worth noting Halotestin was implicated in some early sports doping cases (like Olympic weightlifters in mid-20th century). Today, it’s a specialty steroid – not commonly used due to its harshness, but utilized in specific situations by experienced individuals.
Legal Status
Fluoxymesterone is a prescription drug in the United States (Schedule III controlled substance). It is actually still FDA-approved for male hypogonadism and delayed puberty and for female breast cancer, though in practice doctors rarely prescribe it now given newer therapies. In many other countries, Halotestin has been discontinued or is very limited in medical use (for example, it’s not available in the UK as a prescription anymore). Bodybuilders and athletes obtain it via underground labs or imports. Like all AAS, non-medical use is illegal and banned in sports. WADA prohibits fluoxymesterone; any trace in an athlete’s sample would trigger a violation.
Interestingly, Halotestin’s high prevalence in the 1960s-70s doping scene has waned, but it still appears occasionally in powerlifting or strongman contexts. Legally, possession without a script can lead to penalties similar to other steroids. Halotestin is specifically named in anabolic steroid laws; for example, the DEA’s list of Schedule III anabolic steroids explicitly includes fluoxymesterone. Essentially, it’s treated no differently than other anabolic steroids under the law – although in practice, it’s less common on the black market due to lower demand and higher cost.
Dosing and Administration
Halotestin is taken orally, and tablets are commonly in 5 mg or 10 mg strengths. It is extremely potent; even low doses can have marked effects. Typical athletic dosing ranges from 10 to 40 mg per day. Even 10 mg/day is enough for noticeable strength and aggression increases in many users. A very common protocol is 20 mg/day, split into two 10 mg doses (morning and pre-workout). Some advanced strength athletes push it to 30–40 mg/day, divided into 2-3 doses. Because of its liver toxicity, doses beyond 40 mg and durations beyond 4–6 weeks are strongly discouraged.
Most use Halotestin for short periods – often 2 to 4 weeks is all. For example, a powerlifter might add Halo the last 2-3 weeks before a meet. A contest bodybuilder might use it for the final 4 weeks leading to a show. It’s rarely part of a long cycle from start to finish due to its strain on the liver and lipids. It’s also sometimes used intermittently: e.g. only on heavy training days or only pre-workout at 10–20 mg to get the acute effect. Halo has a short half-life (~9.5 hours), so splitting the dose or timing it strategically (such as 10 mg 2 hours pre-workout) can maximize its benefits when needed and minimize around-the-clock stress.
Halotestin is not typically used by beginners; it’s considered an advanced compound. It’s also not used for bulking since it doesn’t yield weight gain (in fact one might struggle to gain weight on it due to appetite suppression and possible increased fat burning).
Often, Halotestin is stacked with other compounds: - In powerlifting, it may be stacked on a base of testosterone or Deca etc., purely as a finisher to spike strength. - In boxing or MMA (historically), fighters might use low-dose Halo for aggression and strength without adding much weight (useful for staying in a weight class). - In bodybuilding pre-contest, Halo might be combined with other non-aromatizing agents like Trenbolone, Masteron, or Winstrol to maximize muscle hardness and density in the final weeks.
Due to its impact on liver, when Halotestin is introduced, usually any other oral is removed (no one runs two hepatotoxic orals together ideally). The rest of the cycle might be injectables which are less burdensome on the liver.
Subjective Effects
Halotestin is legendary for two primary subjective effects: strength and aggression/energy.
Strength: Users often report explosive strength gains on Halotestin, even in the short term. It’s not uncommon to see personal records being smashed within a couple weeks of starting Halo. Weight for weight, Halo is arguably the most potent strength drug among anabolic steroids (rivaled perhaps only by cheque drops (Mibolerone) or high-dose Anadrol, but Halo’s strength gains come without water weight). Lifters describe the strength increase as “linear and insane” – each workout they feel stronger. One user noted that on 20–30 mg Halotestin, they felt a significant jump in their power on big lifts, far beyond what would be expected from muscle mass alone (this suggests Halo’s neural and aggression components aid in strength expression).
Aggression and Drive: Halotestin has a pronounced effect on mental state. Many users report a heightened aggression, irritability, or intensity. Unlike many steroids that can boost confidence or mild aggression, Halotestin’s effect is often described in more extreme terms: “It makes me care about things a lot more than I otherwise would, making me jealous, angry and resentful… I overreact to things,” said one user reflecting on Halo’s mental side. This indicates that Halotestin can amplify negative emotional responses – a reason it’s considered risky for those not mentally prepared. However, for an athlete about to compete, that aggression can be channeled into performance. Many find during workouts they have a “rage-like focus” – trivial discomforts or fear of big weights vanish, replaced by an almost furious drive to dominate the lift. Another anecdote: “I felt like a real-life Hulk in the gym – zero tolerance for failure, every rep was do-or-die.” Outside the gym, though, that can translate to a short temper or impatience. People often advise avoiding stressful social situations or addressing known triggers while on Halo.
Energy and Fatigue: Some users get a stimulant-like effect – they feel energized and powerful. It’s not an actual stimulant, but the increased androgenic signaling can reduce perceived exertion and increase aggressiveness, which might feel like energy. On the flip side, a few experience fatigue or lethargy, likely due to how harsh Halo is (body is stressed). But overall, it’s known to enhance intensity of training rather than being anabolic in a healing sense.
Muscle Hardness and Density: Halotestin can improve the look of muscles, especially when body fat is already low. It gives a dry, hard appearance – muscles feel very dense and not pumped with water. Bodybuilders in contest prep notice the last few weeks on Halo that they achieve a certain granite-like quality to the muscle, especially combined with low carbs and other cutting drugs. It likely has to do with Halo’s strong androgenic binding in muscle tissue which can lead to temporary strength increase without mass, and possibly some diuretic effect (some report it makes them urinate more or look dryer).
Aggression in the context of sports: For combat sports or intense training, many describe Halotestin providing a competitive aggression. One might feel more “mean” and willing to push through pain or opponent resistance. This is obviously a double-edged sword – if uncontrolled, it could lead to fouls or poor sparring etiquette. There are stories of athletes becoming somewhat reckless or extremely intense under Halo’s influence. It’s sometimes called giving a “killer instinct” boost.
Lack of Mass Gain: Users generally do not feel “bigger” on Halotestin (unlike Dianabol where you feel swole). In fact, weight might not change or can even drop (due to possible reduction in appetite or slight recomposition). Halotestin can sometimes reduce appetite, making it harder to eat big. This is actually helpful for cutting (less hunger on a cut), but not great for bulking. People on Halo cycles often need to force-feed if they want to gain weight – the drug itself isn’t adding size, just strength and hardness.
Miscellaneous: A unique subjective effect: some note their endurance might suffer on Halo, which is interesting because it doesn’t cause water retention. Possibly due to its effect on red blood cells or glucose, some feel they fatigue faster in high-rep sets or cardio. It’s not as notorious as Tren for cardio-killing, but a few have mentioned less stamina on Halotestin – maybe because it’s depleting or doesn’t help pump endurance, being strictly an aggression boost. Another effect: libido can go either way – at low doses, the high androgen often spikes libido, but if it makes one feel generally unwell or if it crushes estrogen too low (since no aromatization), libido can drop. Many on Halotestin also are on a base of testosterone, so usually libido is maintained.
In short, subjective reports sum up Halotestin as making you feel “like a raging bull”: extremely strong, aggressive, focused, and hard, but also with a risk of being on a short fuse and not feeling particularly “healthy” or well (some describe it as having a toxic feeling if run too long, anecdotally a sense of strain on the body, perhaps from blood pressure or liver stress). It’s a specialized drug used when the goal is raw performance and competitive edge rather than general physique building or well-being.
Side Effects
Halotestin’s side effect profile is harsh, reflecting its high androgenicity and oral toxicity:
Hepatotoxicity: Fluoxymesterone is extremely liver toxic. Medical literature and user reports both note significant liver enzyme elevations on even moderate doses. Cases of cholestatic jaundice have been reported in patients on Halotestin. Among oral steroids, Halo is one of the worst for the liver (comparable to or even exceeding Anadrol in toxicity). The 17α-methyl group and its unique structure (fluorination, etc.) make it resilient to hepatic breakdown but very stressful to the liver’s detox pathways. Signs of liver stress like yellowing of eyes, severe fatigue, pain in upper right abdomen, or dark urine are red flags – immediate discontinuation needed if they appear. Because of this, Halotestin cycles are kept very short (2-4 weeks) and alcohol or acetaminophen (Tylenol) are absolutely avoided during use. Liver support supplements (NAC, TUDCA) are strongly recommended. Regular blood tests checking AST/ALT is prudent if using Halotestin, especially beyond 2 weeks. The high liver strain can also contribute to digestive issues and loss of appetite; some feel nauseous or “off” when liver enzymes spike, which on Halo can happen quickly.
Androgenic/Estrogenic: Halotestin does not aromatize to estrogen, so classic estrogenic side effects (gyno, water retention) are basically absent. However, paradoxically, some case reports exist of gynecomastia with fluoxymesterone. This is thought to be due to Halo’s ability to indirectly cause hormonal imbalances (possibly via liver effects raising SHBG or via its minor progestational activity or some downstream metabolite). But in practice, gynecomastia is very rare on Halo and likely due to other stack components. The lack of estrogen can be an issue in itself: very low estrogen from running Halo (especially if someone runs it with non-aromatizing compounds and/or an AI) can lead to joint pain, low libido, and mood issues (estrogen is important for men too in moderation). It’s often wise to ensure some level of estrogen in the body when using Halo – typically by having a baseline of testosterone in the cycle that aromatizes.
The androgenic side effects are pronounced. Acne can flare severely on Halotestin; oily skin is common. Hair loss can accelerate – anyone predisposed to baldness might find their hairline or crown thinning rapidly on Halo (it’s basically like a DHT on steroids in terms of androgenic strength). Prostate enlargement is another risk; older users especially might experience difficulty urinating or increased urge due to prostate swelling from high androgen load. Virilization in women is extremely high risk – Halotestin is absolutely contraindicated for female use in fitness contexts (even at small doses, it would cause deep voice, facial hair, clitoral growth quickly). For men, one notable androgenic effect is aggressive behavior as discussed; some might consider that a “side effect” if it becomes problematic outside the gym. It’s important to monitor mood and perhaps inform close ones that you might be more irritable while on it.
Cardiovascular: Halotestin has a very detrimental effect on cholesterol and cardiovascular health. It tends to crash HDL and skyrocket LDL even more dramatically than many steroids. The mechanism is partly via liver (Halo also uniquely inhibits 11β-HSD2, affecting cortisol and possibly mineralocorticoid balance, which might contribute to hypertension). Users often see blood pressure rise on Halotestin. This can be due to increased hematocrit (some report Halo increases their RBC count modestly, though not as much as EQ or Anadrol) and the stimulation causing vasoconstriction. Also, because Halo can cause anger and stress, that might indirectly raise BP. Headaches and nosebleeds have been noted on Halo cycles, likely from blood pressure spikes. The cardiovascular strain is cumulative: doing multiple Halo cycles or combining it with other harsh compounds can really strain the heart. It’s advisable to use supplements (fish oil, etc.) and a clean diet low in saturated fats to mitigate lipid strain, and keep durations ultra-short. Out of caution, people with any pre-existing heart issues or cholesterol problems should avoid Halotestin entirely.
Psychiatric: The psychological side effects deserve emphasis. Mood swings, aggression, irritability – Halotestin can amplify these significantly. There are accounts of users becoming uncharacteristically angry or even mildly paranoid on Halotestin. In extreme cases, uncontrolled aggression could lead to altercations or accidents. It's crucial to have good self-awareness and, ideally, a controlled environment when using Halo. Some mitigate this by only taking it on workout days or when needed, to avoid being under its influence constantly. After stopping Halo, these mental effects dissipate, but during use they can be among the most immediate sides. On the flip side, if channeled properly (e.g. into training), some count the aggression as a “benefit” – but it’s a fine line and outside of that context, it’s largely a negative side effect.
Others: Because Halotestin is so androgenic, it can cause or worsen insomnia – users often feel “amped up” and may have trouble sleeping, especially if taking it late in the day. It also suppresses appetite, which for a cutting phase might help, but for someone who still needs to eat, it can be an issue (leading to potential weight loss or difficulty maintaining calories). There’s anecdotal notes of weird sweat or odor changes with high androgens (some say Tren or Halo make their sweat smell different – possibly due to metabolic changes). Joint discomfort might arise since no estrogen = less water in joints; some find heavy lifting on Halo can be hard on joints if they’re dry. Also, Halo’s effect on cortisol (via 11β-HSD2 inhibition) can cause a form of mineralocorticoid excess – basically it prevents cortisol from deactivating in the kidneys, which can lead to signs like high blood pressure, electrolyte imbalances, and even fluid retention in some cases (though fluid retention outwardly is not typical, internally the BP can go up).
Suppression: Needless to say, Halotestin will shut down natural testosterone very effectively (it’s an androgen, so via negative feedback it will suppress LH/FSH hard). So, proper PCT is needed if Halo was part of a cycle. Usually Halo is at the end of a cycle, so one would just continue into PCT for the whole cycle.
In summary, Halotestin’s side effects are among the harshest of any anabolic steroid. It’s a “take at your own risk” compound reserved for specific scenarios. Users accept possibly feeling somewhat awful (or at least not healthy) in exchange for peak performance. As one might say, Halo can “make you strong and vicious, but at a cost”. Blood work during a Halo run would typically show dangerously skewed lipids and elevated liver enzymes, underscoring that this is not a steroid for general use or for any extended period.
Common Bodybuilding Use Cases
Strength Sports: Halotestin is most famously used by powerlifters, weightlifters, strongmen, and combat athletes for a short-term boost in strength and aggression. A classic scenario: a powerlifter adds Halotestin in the last 2-4 weeks of meet prep at ~20–30 mg/day. During those weeks, they often report hitting new PRs or that their lifts feel surprisingly lighter. The aggression helps with psyching up for big lifts. Because Halo doesn’t cause weight gain, lifters appreciate that they can gain strength without moving up a weight class (critical when you need to weigh in). For fighters or wrestlers, Halo has been rumored to be taken in the final couple weeks before competition to enhance aggression and strength while possibly even aiding in cutting weight (due to appetite suppression and no water retention). However, its effect on cardio could be a limiting factor for endurance sports.
Contest Prep (Bodybuilding): Some advanced bodybuilders use Halotestin in the final weeks before a show to maximize muscle hardness, density, and to maintain strength on a very calorie-restricted diet. For example, the last 4 weeks they might take 10–20 mg Halo daily. It makes the already lean physique look harder and more vascular. It also can increase aggression for those grueling final workouts when energy is low. It might help drive through fatigue. Stack-wise, Halotestin in contest prep is often combined with other drying agents: e.g. Trenbolone, Masteron, Winstrol – basically no-aromatizing compounds. The cumulative effect yields a very grainy, etched look. Golden Era legend reports claim Halotestin was used by competitors to boost posing aggression and a “warrior mentality” on stage (makes one feel fierce and confident). Modern times, some still do it, although many prefer Anavar or Winstrol if anything, since they are less toxic. But certain elite prep coaches have been known to include a low dose of Halo for the final 10-14 days pre-show for that finishing touch.
Cutting Cycles for Experienced Users: Outside of contest, an experienced lifter might incorporate Halo in a short cutting phase if they want to maintain or increase strength while getting lean. For example, a 6-week mini cut might see Halo in weeks 3-6 to keep strength from plummeting despite being in caloric deficit. The potent androgenic nature of Halo can indeed help preserve muscle and neural strength even when calories are low and one might be low-carb. It’s not common to do a “Halotestin-only” cut (since you’d likely lose muscle if you rely on Halo alone given no anabolic bulk to it), but it could complement a cutting stack primarily for performance maintenance.
Aggression-Boost in Training: There’s anecdotal use of Halotestin as needed – e.g. some may only take it on heavy leg day or a day they plan to attempt a PR. Because of its short action, one could conceivably not take it daily, but say 3 times a week before key training sessions. This way, the liver is given a bit of a break on off days, but the user still harnesses its benefits when it counts. For instance, a powerlifter might do Mon/Wed/Fri heavy lifts and take 10 mg Halotestin those mornings only. This is not a typical regimen but it is mentioned in some circles as a strategy to minimize sides.
Bridging to Meet or Show: Some users who are on injectables might “bridge” the gap between ending injectables and competition day with Halo. For example, if a bodybuilder needs to drop injectables 10-14 days out to let long esters clear (for drug testing or just to drop oil-based injections), they might run Halotestin up to 5 days out (if tested) or even up to the day of show (if untested) to keep strength and hardness. Similarly, a tested powerlifter might drop detectable injectables a few weeks out but use Halo closer to the meet since it’s oral and can clear faster (though any doping use is illegal, this is the tactic some might consider).
Not for Mass: One case where Halotestin is generally not used is in a mass-gaining cycle. It doesn’t significantly help build muscle size and it can reduce appetite and cardiovascular capacity, which actually hinders bulking. Plus, bulking cycles often run longer, which is incompatible with Halo’s short safe usage window. If someone tried to use Halotestin as their main compound to gain muscle, they’d likely be disappointed – they’d get strong but not much bigger, and they would feel bad. Therefore, you’ll almost never see Halo in a classic “off-season bulk” stack (where Dianabol, Anadrol, Deca, etc. rule).
Combos: A potent combination occasionally cited for sheer strength is Halotestin + Trenbolone (with some test base). This is obviously very harsh, but powerlifters chasing ultimate strength have been known to run Tren for its tremendous strength/mass synergy and then add Halo on top for the final push in aggression and neural drive. The user must be extremely careful (as blood pressure and mental side effects can be through the roof with that stack). Another combo is Halotestin + Cheque Drops (Mibolerone) for literally day-of-event aggression (cheque drops are even shorter acting). This was rumored in boxing circles – e.g. take cheque drops 30 minutes pre-fight for insane aggression, and use Halo in the training lead-up. These are anecdotal and dangerous methods reflecting Halo’s niche as an aggression drug.
In conclusion, Halotestin is used sparingly and purposefully: when an experienced user needs that final edge in strength and aggression without adding mass or water. It’s often likened to “nitrous oxide for your body” – a short burst of power that can help win a competition or hit a milestone, but you wouldn’t keep it running in your engine continuously or it’ll blow. The dramatic psychological and performance effects have kept it in the arsenal of some elite athletes, even as most others steer clear of it due to its high risk profile.
Comparative: Halotestin vs Trenbolone (Aggression and Strength)
(A comparison between two of the most notoriously harsh and effective steroids for strength/aggression.)
Compound | Anabolic/Androgenic Rating | Key Effects | Notable Sides | Use Case |
Halotestin (Fluoxymesterone) | ~1900:850 (extremely high, in some assays) | Aggression: Extreme<br>Strength: Extreme<br>Mass: Minimal (dry gains) | Severe liver toxicity, extreme HDL suppression, aggression/irritability, androgenic effects (acne, hair loss). | 2-4 week strength boost or contest hardener when max aggression and strength are needed without weight gain. |
Trenbolone (Tren) | 500:500 (very high) | Aggression: High (but can cause anxiety too)<br>Strength: Very high<br>Mass: Very high (with proper diet) | Night sweats, insomnia (“trensomnia”), high blood pressure, harsh on cardio, tren-cough, prolactin issues, severe HPTA suppression. | Mid/long-cycle powerhouse for recomposition, strength and mass. Often run 6-10 weeks or more; unmatched muscle-building + fat-burning but with heavy sides. |
Discussion: Halotestin vs Trenbolone – Both are known for aggression and strength. Tren is anabolic as well, building lots of muscle and aiding fat loss (“recomp”). Halotestin by contrast doesn’t build much tissue – it’s mostly about immediate strength/aggression. Tren’s aggression often manifests as irritability or anxiety, whereas Halo’s aggression is more anger/drive. Many say Tren makes them easily annoyed and have mood swings, but Halotestin makes them outright rageful if provoked. In terms of strength, Tren gives great strength gains over time (especially with the mass it adds), but Halotestin’s neural impact can sometimes beat Tren’s in short term – like a guy on Test+Tren might add Halo last weeks to lift even more.
Side effect-wise, Trenbolone is overall more multi-faceted in damage (it messes with sleep, cardiovascular, hormones like prolactin, etc.), but Halotestin is acutely more toxic to liver and lipids. Both can significantly raise blood pressure. Tren usually is run longer; Halotestin only short bursts. Some consider Tren sort of a long-term “king of steroids” for transforming physique, whereas Halotestin is a short-term weapon for a specific fight or lift. They’re rarely directly compared because their roles differ, but in contexts like a powerlifting meet prep, one might weigh “Do I use Tren for 8 weeks or Halo for 2 weeks?” – often they actually use both in sequence for maximal effect.
Interestingly, both together are generally not recommended (very harsh synergy on BP and psyche), yet some advanced strength athletes have done it (with test base and careful monitoring).
In summary, Trenbolone is an all-around extremely powerful anabolic-androgenic steroid with significant mass and strength gains (and side effects to match) – used over weeks to reshape one’s body. Halotestin is a specialized, ultra-androgenic steroid used briefly to hit a peak performance metric, with more focused but shorter-term effects. The average gym user will likely never touch Halo, whereas Tren is relatively more common (though still for experienced users). Both require serious respect and are not compounds for beginners by any means.